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Luciferases, fluorescent proteins, nucleic acids encoding the luciferases and fluorescent proteins and the use thereof in diagnostics, high throughput screening and novelty items

DC
  • US 6,232,107 B1
  • Filed: 03/26/1999
  • Issued: 05/15/2001
  • Est. Priority Date: 03/27/1998
  • Status: Expired due to Term
First Claim
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1. An isolated nucleic acid fragment, comprising a sequence of nucleotides encoding a Renilla mulleri luciferase, a Gaussia luciferase or a Pleuromamma luciferase, wherein the sequence of nucleotides is selected from the group consisting ofa sequence of nucleotides set forth in SEQ ID No. 17, SEQ ID No. 19, or SEQ ID No. 28;

  • a sequence of nucleotides encoding the amino acid sequence set forth in SEQ ID No. 18, SEQ ID No. 20 or SEQ ID No. 29;

    or a sequence of nucleotides that hybridizes under high stringency to the sequence of nucleotides set forth in SEQ ID No. 17, SEQ ID No.19 or SEQ ID No. 28.

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