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Orally disintegrable tablets

DC CAFC
  • US 7,875,292 B2
  • Filed: 05/07/2008
  • Issued: 01/25/2011
  • Est. Priority Date: 05/18/1998
  • Status: Expired due to Fees
First Claim
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1. An orally disintegrable tablet which comprises(i) fine granules having an average particle diameter of 400 μ

  • m or less, wherein the fine granules comprise;

    (a) a core composition comprising excipient and 10 weight % or more of an acid-labile physiologically active substance, (b) an enteric coating layer for the core composition, and (c) a coating layer comprising a water-soluble sugar alcohol outside the enteric coating layer; and

    (ii) wherein the additive in (ii) is comprised in the tablet separately from said fine granules in (i) in said tablet and said additive comprises water-soluble sugar alcohol, andwherein oral disintegration time for complete disintegration of the tablet is one minute or less.

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