Treatment of T-cell lymphoma using 10-propargyl-10-deazaaminopterin
First Claim
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1. A method for treatment of T cell lymphoma comprising administering to a human patient diagnosed as having a T cell lymphoma a composition comprising a therapeutically effective amount of 10-propargyl-10-deazaaminopterin.
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Abstract
T cell lymphoma is treated by administering to a patient suffering from T cell lymphoma a therapeutically effective amount of 10-propargyl-10-deazaaminopterin. Remission is observed in human patients, even with drug resistant T cell lymphoma at weekly dosages levels as low as 30 mg/m2. In general, the 10-propargyl-10-deazaaminopterin is administered in an amount of from 30 to 275 mg/m2 per dose.
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8 Claims
- 1. A method for treatment of T cell lymphoma comprising administering to a human patient diagnosed as having a T cell lymphoma a composition comprising a therapeutically effective amount of 10-propargyl-10-deazaaminopterin.
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Granted Patent
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Time in Patent OfficeDays
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Field of Search
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US Class Current514/251
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CPC Class CodesA61K 2300/00 Mixtures or combinations of...A61K 31/519 ortho- or peri-condensed wi...A61K 31/525 Isoalloxazines, e.g. ribofl...A61K 31/7068 having oxo groups directly ...A61P 35/00 Antineoplastic agents
