METHOD AND COMPOSITION FOR ADMINISTERING AN NMDA RECEPTOR ANTAGONIST TO A SUBJECT
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Abstract
The invention provides methods and compositions for administering an NMDA receptor antagonist (e.g., memantine) to a subject.
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Citations
59 Claims
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1-58. -58. (canceled)
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59. A method of achieving a therapeutically effective steady state memantine plasma concentration in less than 20 days of initiation of memantine therapy in a patient that comprises administering an extended release coated pellet capsule formulation of 10-100 mg memantine.
Specification
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Current AssigneeAdamas Pharmaceuticals, Inc. (Supernus Pharmaceuticals, Inc.)
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Original AssigneeAdamas Pharmaceuticals, Inc. (Supernus Pharmaceuticals, Inc.)
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InventorsWent, Gregory T., Fultz, Timothy J., Burkoth, Timothy S., Porter, Seth, Meyerson, Laurence R.
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Granted Patent
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Time in Patent OfficeDays
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Field of Search
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US Class Current424/458
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CPC Class CodesA61K 31/13 Amines A61K31/04 takes prec...A61K 9/4891 Coated capsules; Multilayer...A61P 25/00 Drugs for disorders of the ...A61P 25/02 for peripheral neuropathiesA61P 25/04 Centrally acting analgesics...A61P 25/08 Antiepileptics; Anticonvuls...A61P 25/16 Anti-Parkinson drugsA61P 25/24 AntidepressantsA61P 25/28 for treating neurodegenerat...A61P 25/30 for treating abuse or depen...
